Archives

Page No. : 13-18

ABSTRACT

Bacillus anthracis, a Gram positive bacterium causes a highly dreadful disease and its use as a bioweapon has highlighted the urgent need to understand the pathogenesis and to design effective strategies to combat it. Thus, to develop a highly efficient anthrax vaccine it is essential to understand the protective efficacy and the basis of possible attenuation by characterization of the unstudied B. anthracis strains. Hence, in the current study, an attempt was made to evaluate the characteristics of unstudied IVRI strain by conventional means following comparison with Sterne strain. Simultaneously, antibiogram was also studied, which showed almost similar pattern for both the strains except co-trimoxazole resistance by IVRI strain. In addition, growth pattern studies were also executed in which faster growth rate and short generation time was shown by the IVRI strain.

Keywords: Characterization, B. anthracis, IVRI strain