Archives

Page No. : 110-113

ABSTRACT

Antimicrobial resistance (AMR) is defined as the resistance acquired by the microbes against antimicrobials to which they were once susceptible. AMR is a continuous process taking place in bacterial population via conjugation, transduction and transformation and sometimes by random mutations to cope up with the environmental stress. In the present study we have cultured bacterial isolates from the river Ganga, fl owing through the city Patna, to see the antibiotic resistance profiles of the isolates. We have cultured 128 bacteria from the water samples collected from river Ganga flowing through the city of Patna. The degree of resistance against clindamycin, ciprofloxacin, gentamicin, erythromycin and chloramphenicol observed were 99.2% (127/128), 98.4% (126/128), 95.3% (122/128), 94.5 % (121/128) and 95.3 % (122/128) respectively, whereas 88.2 % (113/128) of isolates were resistant against ampicillin + sulbactam. All the isolates were found to be MDR based on the resistance profile of isolates observed against three or more antibiotics of different classes. Although the study does not reflect the types of bacterial population, the extent of antibiotic resistance in bacterial population observed in the study is threat to public health and needs immediate measures to reduce the development of antibiotic resistance in bacterial population.

Key words: AMR, MDR, Ganga water